Starting with a protein that has been inserted into the Endoplasmic reticulum (ER) membrane with the Amino (N) terminal in the ER lumen and the carboxy (C) terminal in the cytoplasm, describe the journey the protein will take until it is placed in the plasma membrane. Include any modifications that occur during the journey and where they occur. Also, always indicate where the N and C terminal are located.

Answers

Answer 1

Answer and Explanation:

Ribosomes are the primary structure for protein synthesis. They can be found in the rough endoplasmic reticulum or floating in the cytosol.  

Free ribosomes are not attached to any cytoplasmic structure or organelle. They synthesize proteins only for internal cell use. Other ribosomes are attached to the membrane of the endoplasmic reticulum and they are in charge of synthesizing membrane proteins or exportation proteins. Free and attached ribosomes are identical and they can alternate their location. This means that although free ribosomes are floating in the cytosol, eventually, they can get attached to the endoplasmic reticulum membrane.  

Synthesis of proteins that are destined to membrane or exportation starts in the cytoplasm with the production of a molecule portion known as a signal aminoacidic sequence. This signal sequence varies between 13 and 36 amino acids, is located in the amino extreme of the synthesizing protein, and when it reaches a certain length, it meets the signal recognizing particle. This particle joins the signal sequence of the protein and leads the synthesizing protein and associated ribosome to a specific region in the Rough endoplasmic reticulum where it continues the protein building. When they reach the membrane of the endoplasmic reticulum, the signal recognizing particle links to a receptor associated with a pore. Meanwhile, the ribosome keeps synthesizing the protein, and the enlarged polypeptidic chain goes forward the reticulum lumen through the pore. While this is happening, another enzyme cuts the signal sequence, an action that requires energy from the ATP hydrolysis. When the new protein synthesis is complete, the polypeptide is released into the reticulum lumen. Here it also happens the protein folding (which is possible by the formation of disulfide bridges of proteins are formed) and the initial stages of glycosylation (the oligosaccharide addition).  

Once membrane proteins are folded in the interior of the endoplasmic reticulum, they are packaged into vesicles and sent to the Golgi complex, where it occurs the final association of carbohydrates with proteins. The Golgi complex sends proteins to their different destinies. Proteins destined to a certain place are packaged all together in the same vesicle and sent to the target organelle. In the case of membrane proteins, they are packaged in vesicles and sent to the cell membrane where they get incrusted.  

There are certain signal sequences in the carboxy-terminal extreme of the protein that plays an important role during the transport of membrane proteins. A signal as simple as one amino acid in the c-terminal extreme is responsible for the correct transport of the molecule through the whole traject until it reaches the membrane.  


Related Questions

Which cube has a higher surface-area-to-volume ratio?

Answers

Answer:

bottom right ....................

Answer:

4 cm x 4 cm x 4 cm..... .

Explanation:

...

Enzymes are proteins that speed up reactions by

Answers

Answer:

lowering the activation energy needed for the reaction to start

Answer:

lowering the amount of energy required

Explanation:

What is a well-known issue with cross-sectional methodology?

Answers

Answer:

This methodology enables to measure simultaneously both the result and exposure in the group under study

Explanation:

A cross-sectional method is a type of scientific design based on observational data. The cross-sectional studies involve the use of diverse groups that differ in the variable investigated but share other features (for example, individuals with the same educational background, ethnicity, economic status, etc). This class of studies is generally used in developmental psychology.

Which event might occur if the populations of producers in an ecosystem became unstable? A) The direction of energy in the food web would change directions and flow toward the producers. B) Decomposers would become the primary energy source. C) The number of primary consumers would decrease dramatically. D) The energy flow into the food web would decrease or increase along with changing populations of producers. THANK YOU !!! :-)

Answers

Answer:

If the populationsl of producers in an ecosystem became unstable the energy flow into the food web would decrease or increase along with changing populations of producers.

Answer:

Answer: option D.

Explanation:

Hey, there!

Reason: The reason is, when the number of producers are unstable, the flow to enegry from abiotic components to biotic components will be destructed. There will not be proper flow of enegry in whole ecosystem, which usally changes the flow of enegry as per the number of producers.

Hope it helps...

why is still water an ideal enviroment for mold and cast fossils​

Answers

Answer:

Sediment builds up over organisms.

Explanation:

Answer:

Sediment builds up over organisms.

Explanation:

i got it correct on edge nuity

Why must seafood be consumed with caution?
Seafood must be consumed with caution because some fish live in polluted water and _____ A. some people are allergic B, some people are unfamiliar with fish C. some people dislike fish

Answers

A. Some people are allergic

Seafood allergies are deadly

Answer:

first blank: some fish live in polluted water

Second blank: some people are allergic to fish

Explanation:

Plato answer

for edmentum

D)
solid to liquid
Which example shows how a consumer gets energy from food?
A)
a worm eating a dead leaf
B)
a frog laying out in the sun
a rabbit matin

Answers

Answer:

A.

Explanation:

a worm eating a dead leaf, this shows the life process of feeding. Feeding is simply an organism obtainig energy from food. Give me brainliest if i helped!♡

Which agreement led to the reduced release of chemicals that harm the ozone layer?

Answers

Montreal Protocol is the correct answer I think

Answer:

The Montreal Protocol

The Montreal Protocol, finalized in 1987, is a global agreement to protect the stratospheric ozone layer by phasing out the production and consumption of ozone-depleting substances (ODS).

Meter is called a standard unit.Give reason.​

Answers

Answer:

The meter is not called a fundamental unit, except informally by some people. In the International System of units (SI), the meter is one of seven base units. Base units can be defined in terms that do not depend on no units beyond other base units or natural constants (e.g., the speed of light). Using no more than those seven base units, other units can be defined and those are called derived units. No factors or coefficients other than one are used to show how they relate to each other

hope it helps :)

please mark it the brainliest!

Can You Explain it?
Using your textbook page 5 read the context and predict how do you think tomato plants detect pests on a neighboring plant so
they can protect themselves from infestation? Write your prediction in the box below and in your Evidence Notebook.

Answers

Explanation:

Here is my answer from the textbook :)

Answer:

I know that some plants release certain chemicals, taste terrible to pests like the caterpillar, and alert other plants that there are pests around. As a result of this, when other plants detect the chemical released, they work together towards a solution.

Nitric acid is a chemical that is used in the production of fertilizers. The chemical formula of nitric acid is
HNO3
Which of the following are true for a nitric acid molecule?
Select all that apply.
A. It has three atoms.
B. It has three different types C. of atoms.
D. It has three oxygen atoms.

Answers

Answer:

D is the right answer

Explanation:

Answer:

It has three atoms.

It has three oxygen atoms.

Explanation: I just took the test :D

If I put 1 mole of substance A and 2 moles of substance B into 1 liter of water, which
of the following best describes what I have made?

Answers

Answer:

molar masses

Explanation:

g What are the three basic assumptions of Darwinian evolution? Group of answer choices Presence of phenotypic variation, some phenotypic variation due to genetic variation, the given trait has an impact on fitness Presence of phenotypic variation, environmental variation, the given trait has no impact on fitness Presence of phenotypic variation, environmental heritability, the given trait has an impact on fitness Presence of phenotypic variation, trait present in only the mitochondrial DNA, the given trait has an impact on fitness

Answers

Answer:

1- Presence of phenotypic variation

2- some phenotypic variation due to genetic variation

3- the given trait has an impact on fitness  

Explanation:

The evolutionary theory by natural selection proposed by Darwin in his publication “On the origin of species” (1859) is based on a series of assumptions that enable to understand the amazing biodiversity on the Earth. First, individuals are not identical among them, i.e., there exists variation in the traits among the members of a given population, species, etc. Second, phenotypic variation leads to differential survival and reproduction of the organisms that are best fitted to the environment (i.e., competence among the members of the population). Finally, phenotypic traits are passed from generation to generation (i.e., phenotypic variation is inheritable), thereby favoring offspring from parents more adapted to the environment.

An experiment was performed to measure the growth of bacterial colonies on an agar plate over a 48- hour period. Which type of graph or chart would be most suitable to represent the data. PLEASE HELP! THE ANSWER CHOICES ARE A: Pie chart B: Bar graph C: Stacked bar graph D: Line graph! This is 8th-grade science help:C

Answers

Answer:

D. Line graph

Explanation:

A line graph is used to track changes over short or long periods of time

the other options don’t make sense other than the bar graph but you are not comparing anything and it just makes more sense to use a line graph.

In which of the following biomes is annual precipitation lowest?a. tundrab. taigac. grasslandd. temperate deciduous foreste. tropical rain forest

Answers

Answer: Option A.

Tundra

Explanation:

Tundra biome have the lowest annual precipitation because it is the coldest of all the biomes and it is plain without trees and have frost molded land scape. It have low or poor nutrients which do not support plants growth, low temperature or have the lowest temperature, little precipitation and short growing seasons.

It's annual precipitation is less than 25 centimeter annually and they are also considered as desert, after the short growing seasons, it is followed by harsh conditions which the plants and animals present there posses a special type of adaptation for survival in the area. They are found in high altitude landmass such as Canada, Russia, Alaska e.t.c.

use an outline to explain
anaerobic respiration​

Answers

Answer:

Anaerobic respiration is used commercially in the production of beer, wine, bread, yogurt, and cheese.

Hope this helps :)

Anaerobic respiration transfers energy from glucose to cells. It occurs when oxygen is not present. It transfers large amounts of energy quickly. In anaerobic respiration, glucose breaks down without oxygen. The chemical reaction transfers energy from glucose to the cell. Anaerobic respiration produces lactic acid, rather than carbon dioxide and water. Unfortunately this can lead to painful muscle cramps.

What is the relationship between combustion and plants? (Using the picture)

HELP ILL MARK YOU BRAINLIEST

Answers

During photosynthesis, plants use carbon dioxide and produce oxygen. During metabolism oxygen is used and carbon dioxide is a product. Humans impact the carbon cycle during the combustion of any type of fossil fuel, which may include oil, coal, or natural gas

Examine the label information on the packages of a variety of breakfast cereals. Which types of cereals provide the best sources of carbohydrates, lipids, proteins, vitamins, and minerals? Which major nutrients are lacking in these cereals?

Answers

Answer:

B

Explanation:

B

In a fluorescence recovery after photobleaching (FRAP) experiment, a fluorescently tagged membrane protein, A, shows very little recovery of fluorescence ten minutes after photobleaching, while membrane protein B shows a rapid increase in fluorescence after bleaching, recovering nearly 80% of its original fluorescent signal by ten minutes. Based on this information, which of the following statements can be made?
A. Proteins A and B interact with each other in a complex
B. Protein A is easily denatured,
C. Protein Bis diffusing in a more fluid membrane.
D. Protein Ahas faster mobility in the membrane.

Answers

Answer:

The correct answer is option C.  Protein Bis diffusing in a more fluid membrane.

Explanation:

Fluorescence recovery after photobleaching or FRAP is a technique used to examine the portability of fluorescent particles with the help of fluorescence microscopy that have been utilized since the mid-70s to evaluate the dispersion or movements of molecules in the cell membranes of the cell.

Fluorescence Recovery After Photobleaching (FRAP) is a strategy for deciding the energy of dispersion in living cells (typically) utilizing fluorescence microscopy.

In the given experiment:

The diffusion coefficient of GFP vary, based on the localization of the protein

Protein B is freely diffusing, due to which recovery is very high compared to protein A.

Protein which is less diffusing shows a slower and less rate of recovery.

As the adrenal gland releases glucocorticoids, which of the following effects may be observed? a) Increased blood levels of amino acids
b) Decreased blood pressure and volume
c) Decrease in immune system function
d) Lipid breakdown in the liver will increase
e) Increased water absorption in the kidney
f) Increased blood glucose levels

Answers

Answer:

The correct option is F) Increased blood glucose levels

Explanation:

The release of glucocorticoids into the body is part of the body's chemical process for managing stress and ultimately prepares the body for fight or flight.

The body anticipates that it may consume additional fuel/energy during elevated stress levels, it therefore through the adrenal cortex which is situated above the kidneys, sends glucocorticoids into the body.

The glucocorticoids trigger the body's metabolism with regard to breaking down stored fuel in order to produce the required energy that it needs.

Cheers!

How is Twain effective at using humor? Cite evidence of humorous moments in the text. Also consider Twain’s intent and viewpoint in your response.

Answers

Twain is effective at using his humor because he uses it to entertain his readers. It makes his readers laugh and provides social criticism mixed with humor. Twain shows the dark side of human nature in a funny way and expresses a serious viewpoint through silly characters.

Humor is the use of words, actions or signals which elicit laughter or smiles in a good natured way from people.

There are different scenarios where humor can be used effectively such as:

To bring relief to a tense atmosphere To make a room more livelyTo bring happiness to a person, etc

With all these in mind, Twain could have been effective at using humor because he knew just the right moment to be humorous and he was able to say the right things at the right time.

Please note that your question is incomplete, and as a result, i gave you a general overview to help you get the right answer.

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How does the injection of insulin affect the signal transduction pathway of type 1 diabetics?
a. Injected insulin prevents the glucose from binding to cellular protein receptor.
b. Insulin acts as a secondary messenger that cascades the message to allow glucose into the cell.
c. Insulin is absorbed into the cytoplasm and binds with the transcription factor to make it active.
d. Protein receptors on the cell bond to the insulin, which allows glucose to enter the cell.

Answers

Answer:

The correct answer is D.

Explanation:

To act on target cells, insulin binds to a specialized protein that is located on the membrane of your target cells: the insulin receptor. When insulin binds to the receptor, it activates a cascade of signals within the cell (a process called signal transduction), which is essential for insulin to have an effect on its target tissues. Insulin increases the entry of glucose into cells and causes the number of certain proteins specialized in glucose transport to increase in the membrane of their target cells, such as adipocytes (adipose tissue cells) and skeletal muscle cells.

Answer:

The correct answer is B, b. Insulin acts as a secondary messenger that cascades the message to allow glucose into the cell.

Tessa conducted a demonstration about the movement of materials in and out of cells. She closed the door to her classroom, then sprayed a little perfume in the corner of the room. She drew this diagram to represent the room, with the dots representing the perfume molecules. Which statement best describes what Tessa should tell the class about the diagram? Diffusion has already occurred. Diffusion will occur. Active transport has already occurred. Active transport will occur.

Answers

Answer:

Diffusion has already occurred.

Explanation:

Answer:

diffusion has already occured

Explanation:

i took the ed test

Which nerve is responsible for weakness in climbing stairs or jumping?
A. Tibial
B. Superior gluteal
C. Inferior gluteal
D. Obturator
E. Femoral

Answers

Answer:

C. Inferior gluteal

Explanation:

The inferior gluteal nerve has a rich concentration in the gluteus maximus muscle. This muscle is located in the hip region. These nerves are primarily responsible for the ability of the gluteus maximus to move and performs some functions during motion.

An example of such function involves the extension of the hip to the thigh in movements such as climbing stairs, hiking, squatting etc.

Look at the graphic in the section "What Are the Steps In The Scientific Method?"

According to the article, what is represented by the step called "Hypothesis"?

Answers

Answer:

Brief description of the Orginal experiment state what was done

Explanation:

What did you change?

How did the changes help answer the question

22.Which among the following is not the mode of excretion in plants?

(1 Point)

Diffusion

Stores the waste in dead permanent tissue

Nephridia​

Answers

Answer:

Nephridia

Explanation:

diffusion helps liquid and gas in to speed up the rate of higher concentration to the region of lower concentration...

The relative concentration of each in the plasma membrane is partly regulated by the:_______

Answers

Answer:

ion channels

Explanation:

The plasma membrane plays a critical role in regulating and maintaining ionic potential inside the cell, relative to ionic concentration present outside the cell. The ion channels are specific, in that they only recognize and allow particular ions to pass through and block the rest. Their opening and closing depends on the ionic potential during that time period.

A mutation occurs, and cytosine is replaced with adenine. What impact do you think this will have on the DNA structure?

Answers

Adenine is larger than cytosine and will not be able to base pair properly with the guanine on the opposing strand. This will cause the DNA to bulge.

Adenine is larger than Cytosine base pair which make it unable to base pair properly with the guanine on the opposing strand. This will cause the DNA to bulge.

What is Mutation?

Mutation refers to a sudden change. It is a change in the nucleic acid sequence of an organism's genome. This results in changes to the cell's DNA sequence that can be caused by mistakes during cell division, or by exposure to DNA-damaging agents in the environment.

There are two major types of mutations which are:-

1. Germline mutations

This type of mutation occur in gametes

2. Somatic mutations

This type of mutation occur in other cells of the body.

There are also some types of mutations that are found. They are

1. Base substitutions

2. Deletions

3. Insertions.

Thus, Adenine is larger than Cytosine base pair which make it unable to base pair properly with the guanine on the opposing strand. This will cause the DNA to bulge.

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What organ system maintains blood oxygen and carbon dioxide levels?

Answers

Answer respiration system

Explanation:

cause

What important function do stream pools serve?
a. Stream pools serve as a habitat for juvenile fish.
b. Stream pools serve as a habitat for organisms that have difficulty in feeding or navigating
swifter areas of the stream.
c. They have greater depth and lower velocity than other parts of the stream, thus allowing a
habitat for organisms during dryer seasons.
d. All of the above

Answers

Answer:

D. All the above

Explanation:

The important function of stream pool are;

Stream pools serve as a habitat for juvenile fish.Stream pools serve as a habitat for organisms that have difficulty in feeding or navigating

swifter areas of the stream.

They have greater depth and lower velocity than other parts of the stream, thus allowing a

habitat for organisms during dryer seasons

What is stream pool?

Stream pool refers to an extension or stretch of a river or stream in which the water goes deep and the depth is above average of other water source and the water velocity is also.below average.

Stream pool is formed from beddings of sediments or can be armoured with gravel.

Therefore, the important of stream pool are;

Stream pools serve as a habitat for juvenile fish.Stream pools serve as a habitat for organisms that have difficulty in feeding or navigating

swifter areas of the stream.

They have greater depth and lower velocity than other parts of the stream, thus allowing a

habitat for organisms during dryer seasons

Learn more about stream pool from the link below.

https://brainly.com/question/1285201

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